Ohmic‐assisted hydrodistillation of essential oils from Zataria multiflora Boiss (Shirazi thyme)

Ohmic‐assisted hydrodistillation (OAHD) is a combination of ohmic heating and distillation, and could be considered as a novel method for the extraction of essential oils. Major problems with traditional methods are long extraction time and lower purity of the extract. In this study, OAHD was applied as an economic and green technology for the extraction of essential oils from Zataria multiflora Boiss. (Shirazi thyme) aerial parts and the results were compared to those obtained from hydrodistillation (HD) as a conventional method. The results showed that OAHD method had the extraction time of 32.21 ± 2.59 min while this value was about 57.21 ± 2.33 min for hydrodistillation (HD). Scanning electron micrographs of thyme leaves showed a sudden eruption of essential oil glands and their surrounding area for OAHD samples. GC–MS analysis indicated that both methods of OAHD and HD can extract the same compounds.     

Development of Turbulent Wakes Evolving from Asymmetric Shear Layers

ABSTRACT

This paper reports an experimental investigation on the response of a turbulent wake past an elongated flat plate to various upstream flow conditions Different tripping wires were placed on the upper side of the plate downstream the leading edge resulting in asymmetric shear layers evolving from the trailing edges. Mean flow and turbulent fields of the asymmetric wakes were compared to their symmetrical counterpart. The symmetrical wake was found to attain a self-similar state whereas asymmetric wakes continued to slowly evolve towards an expected asymptotic behavior at a rate that strongly depends on the imposed initial conditions.     

Multi-criteria expertness based cooperative Q-learning

One of the most influential points in cooperative learning is the type of exchanging information. If the content of exchanging information among agents is rich, cooperation gives rise to better results. To extract proper knowledge of agents during the cooperation process, some expertness measures that assign expertness levels to the other agents are used. In this paper, a new method named Multi-Criteria Expertness based cooperative Q-learning (MCE) is proposed that utilizes all of the expertness measures and attempts to enrich the exchanging information more efficiently. In MCE, all expertness measures are considered simultaneously and collective knowledge is equal to the combination of learned knowledge by each of expertness measures. The experimental results confirm outstanding performance of the proposed method on a sample maze world and a hunter-prey problem.     

Theoretical challenges in understanding the inhibition mechanism of aluminum corrosion in basic media in the presence of some p-phenol derivatives

Using quantum electrochemical/thermodynamical approaches based on coupled cluster/polarized continuum models and density functional theory (CM/PCM–DFT), we investigated the corrosion inhibition mechanism of Al/NaOH system in the presence of some p-phenol derivatives. The influencing parameters on inhibitory action, i.e. charges on oxygen and hydrogen atoms of hydroxyl group, charge transfer, interaction energy, molecular activity and softness, electric dipole moment and de-solvation free energy, were determined for both neutral and deprotonated species at metal|solution interface. A good correlation was observed between these parameters and inhibition efficiency data reported in the literature. By introducing an appropriate thermodynamic procedure, we also determined the proton-loss tendency of the molecules nearby interface. The results were amazing and revealed a complicated protonation/deprotonation cycle for inhibitor species inside electrical double layer; the corrosive agents in the vicinity of metal surface become locally neutralized and pushed away.     

Poly(glycerol sebacate) nanoparticles for ocular delivery of sunitinib: physicochemical,cytotoxic and allergic studies

Poly(glycerol sebacate) (PGS) is a new biodegradable polymer with good biocompatibility used in many fields of biomedicine and drug delivery. Sunitinib‐loaded PGS/gelatine nanoparticles were prepared by the de‐solvation method for retinal delivery and treatment of diabetic retinopathy. The nanoparticles were characterised by Fourier‐transform infrared and differential scanning calorimetry. The effects of different formulation variables including drug‐to‐carrier ratio, gelatine‐to‐PGS ratio, and glycerine‐to‐sebacate ratio were assessed on the encapsulation efficiency (EE%), particle size, release efficiency (RE), and zeta potential of the nanoparticles. The in vitro cytotoxicity of PGS/gelatine nanoparticles was studied on L929 cells. Draize test on rabbit eyes was also done to investigate the possible allergic reactions caused by the polymer. Glycerine/sebacic acid was the most effective parameter on the EE and RE. Gelatine‐to‐PGS ratio had the most considerable effect on the particle size while the RE was more affected by the glycerine/sebacic acid ratio. The optimised formulation (S₁ G_0.7 D_21.2) exhibited a particle size of 282 nm, 34.6% EE, zeta potential of −8.9 mV, and RE% of about 27.3% for drug over 228 h. The 3‐(4,5‐dimethylthuazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assay indicated PGS/gelatine nanoparticles were not cytotoxic and sunitinib‐loaded nanoparticles were not toxic at concentrations <36 nM.Inspec keywords: polymers, differential scanning calorimetry, toxicology, drug delivery systems, solvation, eye, encapsulation, particle size, drugs, biodegradable materials, nanofabrication, nanomedicine, nanoparticles, gelatin, Fourier transform infrared spectraOther keywords: gelatine‐to‐PGS ratio, glycerine‐to‐sebacate ratio, particle size, zeta potential, sunitinib‐loaded nanoparticles, biodegradable polymer, retinal delivery, differential scanning calorimetry, drug‐to‐carrier ratio, allergic reactions, physicochemistry, cytotoxicity, poly(glycerol sebacate) nanoparticles, sunitinib ocular delivery, drug delivery, sunitinib‐loaded PGS‐gelatine nanoparticles, Fourier‐transform, in vitro cytotoxicity, biocompatibility, Draize test, rabbit eyes, 3‐(4,5‐dimethylthuazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assay     

Aluminum Pitting Corrosion in Halide Media: A Quantum Model and Empirical Evidence

The phenomenon of localized damage of aluminum oxide surface in the presence of halide anions was scrutinized at an atomistic level, through the cluster approach and density functional theory. The phenomenon was also investigated empirically through Tafel polarization plots and scanning electron microscopy. A distinct behavior witnessed in the fluoride medium was justified through the hard-soft acid-base principle. The atomistic investigations revealed the greatest potency for chloride entrance into the metal oxide lattice and rationalized to the severity of damage. The interaction of halide anions with the oxide surface causing some displacements on the position of Al atoms provides a mechanistic insight of the phenomenon.     

Hydrogen storage in bulk Mg-Ti and Mg-stainless steel multilayer composites synthesized via accumulative roll-bonding (ARB)

We have tested the hydrogen storage cycling behavior of bulk centimeter-scale magnesium - titanium and magnesium - stainless steel multilayer composites synthesized by accumulative roll-bonding (ARB). Roll-bonding of either titanium or stainless steel with magnesium allows the reversible hydrogen sorption of the resulting composite at 350 °C. Identically roll-bonded pure magnesium can hardly be absorbed at this temperature. In the composites, the kinetics of the first cycle of absorption (also called “activation”) improves with increased number of fold and roll (FR) operations. With increasing FR operations the distribution of the Ti phase is progressively refined, and the shape of the absorption curve no longer remains sigmoidal. Increasing the loading amount of the second phase also accelerates the kinetics. This holds true up to a threshold limit. Microscopy analysis performed on 1-2 wt.% hydrogen absorbed composites demonstrates that MgH₂ formed exclusively on various heterogeneous nucleation sites. During activation, MgH₂ nucleation occurred at the Mg-hard phase interfaces. During the subsequent absorption cycles, heterogeneous nucleation primarily occurred in the vicinity of “internal” free surfaces such as cracks.     

Dynamic TDD Fixed Cellular Systems Using Smart and Sectored Antennas

There are many benefits in using time division duplex (TDD) instead of frequency division duplex (FDD) schemes in fixed wireless cellular systems. For example, channel reciprocity for a single carrier frequency used on both uplinks and downlinks will allow easy access to channel state information, reduced complexity of RF design, much higher flexibility in handling dynamic traffic, simpler frequency plan, etc. However, there exists a serious limiting factor in using dynamic TDD (D-TDD) in cellular systems. This is due to a steady interference on an uplink in any cell caused by downlink transmissions in other cells. Simulation results show in D-TDD cellular systems, performance is unacceptable, when an omnidirectional antenna is used at base stations. Simulation results also suggest great potential for smart antennas in achieving substantial performance improvement in fixed D-TDD bandwidth-on-demand wireless systems.     

Identification of time-varying linear and bilinear systems via Fourier series

A method for identification of time-varying linear systems and bilinear systems is proposed. The method is based upon expanding various time functions in the system as their truncated Fourier series, using the operational matrices for integration and product and hence reducing the problem into a set of algebraic equations. The method is computationally attractive, and applications are demonstrated through illustrative examples.